Eight-Stage Andersen Cascade Impact Sampler (ACI)

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Eight-Stage Andersen Cascade Impact Sampler (ACI) is a multi-stage, porous device designed to analyze the aerodynamic properties of inhalable fine particles. It features multiple cascade impactors and a membrane in the final stage.

For MDI and spray testing, the top cover connects to an artificial larynx and generator using an adapter. For DPI testing, a pre-separator should be installed on the top layer to capture large amounts of non-inhalable powder particles. The sampler complies with USP, Ph. Eur., and ChP 2020 standards for aerodynamic characterization of inhaled fine particles.

Standards

  • United States Pharmacopeia (USP) <601> Aerosols, Nasal Sprays, Metered-Dose Inhalers, and Dry Powder Inhalers
  • European Pharmacopoeia (Ph. Eur.) 2.9.18: Preparations for Inhalation - Aerodynamic Assessment of Fine Particles
  • Chinese Pharmacopoeia (ChP) 2020 - Inhalation Product Testing

Eight-Stage Andersen Cascade Impact Sampler (ACI)

28.3L/min configuration

Eight-Stage Andersen Cascade Impact Sampler (ACI)

60L/min configuration

Eight-Stage Andersen Cascade Impact Sampler (ACI)
90L/min configuration

 

  1. Pre-separator ensures accurate separation of coarse particles.
  2. Sampling flow rate: 28.3L/min (optional 60L/min, 90L/min).
  3. Low cost and easy operation.
  4. Effectively eliminates particle rebound and entrainment.
  5. USP, Ph. Eur. and ChP compliant.

CategorySpecifications
Main Components9 stainless steel impactors
9 stainless steel collection cups
1 induction port
1 pre-separator
Sampling Particle Size0.4 - 9 micron
DimensionsImpactor: φ97mm × 221mm
Pre-separator: φ76mm × 148mm
WeightTotal: 8.1kg
(Impactor: 5.1kg, Pre-separator: 1.6kg, Induction port: 1.4kg)

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