Dissolution Tester

Dissolution Testers | USP <711> & Ph.Eur. 2.9.3 Pharmaceutical Quality Control

Dissolution testers measure how solid oral dosage forms release their active pharmaceutical ingredient into a defined medium under controlled hydrodynamic conditions. Built to USP <711> and Ph.Eur. 2.9.3, they support batch release quality control, formulation development, and bioequivalence studies across pharmaceutical manufacturers, contract testing laboratories, and regulatory-compliant R&D programs.

The Torontech range covers standalone dissolution baths, integrated autosampled systems, and single-vessel R&D testers, so you can match the workstation to your throughput, sample volume, and workflow.

Applications

Dissolution testing supports quality control, formulation, and regulatory workflows across pharmaceutical development and manufacturing.

Batch Release Testing: routine dissolution QC of tablets, capsules, and coated dosage forms per USP <711> paddle and basket methods.
Generic Drug Development: comparative dissolution profiling against reference-listed drug products for ANDA submissions and f2 similarity factor calculations.
Formulation Development: excipient screening, compression parameter studies, and matrix optimization during early tablet design.
Extended-Release Product Testing: multi-point dissolution profiles over 12 to 24 hour runs for controlled and delayed-release dosage forms.
Stability Program Testing: dissolution performance monitoring under ICH storage conditions for shelf-life determination.
Bioequivalence Studies: multi-media profile generation for BCS-classification workflows and biowaiver applications.
Contract Testing Laboratories: audit-trail-backed dissolution analysis for CRO and CDMO clients requiring full documentation packages.
Method Development: parameter screening across media, apparatus, and rotation speed to establish discriminating dissolution methods.

Dissolution Tester Range

The Torontech dissolution tester lineup groups into three configurations: fully integrated autosampled systems, standalone dissolution baths with manual or upgradable sampling, and a single-vessel unit for method development. Match the configuration to your workflow first, then the vessel count to your daily throughput.

Automated Dissolution Systems

Combined dissolution baths with fully integrated autosampling for hands-off operation from method start through vial collection.

Automated Dissolution System - ToronDISS™ A12

A 12-vessel dissolution tester with an integrated autosampler, engineered for high-throughput pharmaceutical QC labs running two parallel USP six-vessel batches. The platform handles method setup, temperature control, sampling schedules, and vial collection from a single interface, and suits busy release-testing operations, CRO workflows, and stability campaigns requiring multi-point overnight sampling.

Dissolution Autosampler - ToronDISS™ A8

An 8-vessel dissolution tester with a fully integrated automatic sampling module, sized for a standard USP six-vessel batch with two spare stations for method verification. The autosampler withdraws, filters, and dispenses aliquots into positioned vials without operator intervention, cutting the manual pipetting steps that limit reproducibility on traditional dissolution workflows.

Standalone Dissolution Testers

Multi-vessel dissolution baths with manual sampling manifolds, some of which support an optional autosampler upgrade path.

12-Vessel Dissolution Tester - ToronDISS™ 12

A 12-vessel standalone dissolution bath for labs running two concurrent USP six-vessel batches without an integrated autosampler. Independent temperature regulation on each cell, three-tier user access, and audit trail logging suit high-volume batch release testing and stability programs, with an optional autosampling module available for future workflow automation.

8-Vessel Dissolution Tester - ToronDISS™ 8

An 8-vessel dissolution bath with modular sampling components, independent per-cell temperature probes, and an autosampler upgrade path. The configuration matches the standard USP six-vessel protocol with two spare stations, and suits mid-throughput QC labs planning to automate later without replacing the base bath.

Automated 8-Vessel Dissolution Tester - ToronDISS™ 8I

An 8-vessel dissolution tester with a factory-optional mini-paddle accessory kit for small volume dissolution testing of low-dose and high-potency drug products. Three-tier operator access and timestamped audit trails support GMP release testing, and the mini-paddle option preserves USP Apparatus 2 hydrodynamics on high-potency APIs where standard 900 mL vessels dilute below detection.

6-Vessel Dissolution Tester - ToronDISS™ 6I

A 6-vessel dissolution tester matching the standard USP six-vessel protocol in a compact benchtop workstation, with optional 150 mL small volume vessels and mini-paddle accessories for low-dose testing. The format suits R&D labs, biopharmaceutical developers, and QC operations that need pharmacopoeial capacity plus dedicated small-volume capability without a second instrument.

Single-Vessel R&D Dissolution Tester

Compact single-cell testers built for method development, exploratory studies, and academic research where a multi-vessel bath exceeds daily testing volume.

Single-Vessel Dissolution Tester - ToronDISS™ 1

A single-vessel dissolution tester with automated cup and paddle centering, a touchscreen interface, and full IQ/OQ documentation for R&D and method development labs. The automated centering system removes the largest source of manual apparatus qualification error, and the compact benchtop footprint fits shared bench space in academic labs, compounding pharmacies, and formulation development groups.

How to Choose the Right Dissolution Tester

For fully hands-off automated testing: choose an autosampled system (ToronDISS™ A12 for high-throughput 12-vessel operations, ToronDISS™ A8 for standard USP six-vessel workflows).
For high-throughput standalone dissolution testing: choose the ToronDISS™ 12 for two concurrent USP six-vessel batches without autosampling.
For standard USP six-vessel batch release: choose the ToronDISS™ 8 with modular sampling and an autosampler upgrade path for future automation.
For low-dose or high-potency drug product testing: choose the ToronDISS™ 8I or ToronDISS™ 6I with mini-paddle and small-volume vessel options.
For compact benchtop USP six-vessel workflows: choose the ToronDISS™ 6I for standard protocol testing with a smaller footprint than an 8 or 12-vessel bath.
For method development and R&D: choose the ToronDISS™ 1 single-vessel tester for exploratory studies, formulation screening, and apparatus calibration verification.

Why Choose Torontech for Your Dissolution Tester

Torontech supplies testing and measurement equipment to laboratories and manufacturers across North America and worldwide, backed by responsive technical support and calibration service. The dissolution tester range is built for reliable, standards-driven results, so you can standardize on one supplier as your testing needs grow. Our team helps you match the right configuration to your samples, applicable standards, and throughput, then supports you through installation and beyond.

Request a Quote

Tell us your product type, expected daily throughput, and whether you need autosampling or R&D flexibility, and we will recommend the right dissolution tester. Contact the Torontech team for pricing, lead times, and IQ/OQ documentation.