Dissolution Tester

Dissolution Testers | USP <711> & Ph.Eur. 2.9.3 Pharmaceutical Quality Control

Dissolution testers measure how solid oral dosage forms release their active pharmaceutical ingredient into a defined medium under controlled hydrodynamic conditions. Built to USP <711> and Ph.Eur. 2.9.3, they support batch release quality control, formulation development, and bioequivalence studies across pharmaceutical manufacturers, contract testing laboratories, and regulatory-compliant R&D programs.

The Torontech range covers standalone dissolution baths, integrated autosampled systems, and single-vessel R&D testers, so you can match the workstation to your throughput, sample volume, and workflow.

Applications

Dissolution testing supports quality control, formulation, and regulatory workflows across pharmaceutical development and manufacturing.
Batch Release Testing: routine dissolution QC of tablets, capsules, and coated dosage forms per USP <711> paddle and basket methods.
Generic Drug Development: comparative dissolution profiling against reference-listed drug products for ANDA submissions and f2 similarity factor calculations.
Formulation Development: excipient screening, compression parameter studies, and matrix optimization during early tablet design.
Extended-Release Product Testing: multi-point dissolution profiles over 12 to 24 hour runs for controlled and delayed-release dosage forms.
Stability Program Testing: dissolution performance monitoring under ICH storage conditions for shelf-life determination.
Bioequivalence Studies: multi-media profile generation for BCS-classification workflows and biowaiver applications.
Contract Testing Laboratories: audit-trail-backed dissolution analysis for CRO and CDMO clients requiring full documentation packages.
Method Development: parameter screening across media, apparatus, and rotation speed to establish discriminating dissolution methods.

How to Choose the Right Dissolution Tester

For fully hands-off automated testing: choose an autosampled system (ToronDISS™ A12 for high-throughput 12-vessel operations, ToronDISS™ A8 for standard USP six-vessel workflows).
For high-throughput standalone dissolution testing: choose the ToronDISS™ 12 for two concurrent USP six-vessel batches without autosampling.
For standard USP six-vessel batch release: choose the ToronDISS™ 8 with modular sampling and an autosampler upgrade path for future automation.
For low-dose or high-potency drug product testing: choose the ToronDISS™ 8I or ToronDISS™ 6I with mini-paddle and small-volume vessel options.
For compact benchtop USP six-vessel workflows: choose the ToronDISS™ 6I for standard protocol testing with a smaller footprint than an 8 or 12-vessel bath.
For method development and R&D: choose the ToronDISS™ 1 single-vessel tester for exploratory studies, formulation screening, and apparatus calibration verification.

Why Choose Torontech for Your Dissolution Tester

Torontech supplies testing and measurement equipment to laboratories and manufacturers across North America and worldwide, backed by responsive technical support and calibration service. The dissolution tester range is built for reliable, standards-driven results, so you can standardize on one supplier as your testing needs grow. Our team helps you match the right configuration to your samples, applicable standards, and throughput, then supports you through installation and beyond.

Request a Quote

Tell us your product type, expected daily throughput, and whether you need autosampling or R&D flexibility, and we will recommend the right dissolution tester. Contact the Torontech team for pricing, lead times, and IQ/OQ documentation.